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Immunology [1]

Paper Code: 
AMB 401
Credits: 
03
Contact Hours: 
45
Objective: 

 

This paper will enable students to-
  • learn the fundamentals of immune system
  • study the various cellular and molecular aspects of immune system
  • understand the regulation of immune response 
  • learn various immunological diagnostic techniques
8.00
Unit I: 
Basic Immunology

 

Introduction to immune system- Phylogeny of immune system, Innate and acquired immunity
Cells of the Immune system: Hematopoiesis and differentiation, B-lymphocytes, T-lymphocytes, Macrophages, Dendritic cells, NK cells, Eosinophils, Neutrophils and Mast Cells
Organization and structure of lymphoid organs
11.00
Unit II: 
Cellular and molecular aspects

 

Nature and biology of antigens and super antigens
Immunoglobulin: structure, types and their function
MHC, B and T-Cell Receptor
Complement system
10.00
Unit III: 
Immune response & its regulation

 

Generation of Humoral and Cell mediated immune responses
B- and T- cell maturation, activation and differentiation
Cytokines and their role in immune regulation
T-cell regulation, MHC restriction
Immunological tolerance
7.00
Unit IV: 
Antigen- antibody interactions

 

Antigen processing and presentation
Precipitation, Immunodiffusion, Immunoelectrophoresis, Agglutination, RIA, ELISA, Immunofluorescence
9.00
Unit V: 
Selected concepts in Immunology

 

Hypersenstivity
Autoimmunity
Tumor Immunology
AIDS and other immunodeficiencies
ESSENTIAL READINGS: 

 

1. Kuby Immunology, 4th edition- R.A. Goldsby and others, Freeman & Co., New York, 2001
2. Roitt’s, Essential Immunology, 10th edition, Ivan M Roitt and Peter J Delves, Blackwell Science, 2001
3. Instant Notes on Immunology, 2nd edition, Lydyard, Wheran and Fanger, Viva Books Pvt. Ltd., 2003
REFERENCES: 

 

1. Cellular and Molecular Immunology, 3rd edition, Abbas, Litchman and Pober, Harcourt Brace and Company, 1998
2. Immunology: A Comprehensive Review, Darla J. Wise and Gordon R. Carter, Iowa State University Press, 2001
3. Medical Microbiology and Immunology: Examination and Board Review, 7th edition,Warren Levinson and Ernst Jawetz, Mc Graw Hill, 2002
Academic Year: 
2018-2019 [2]

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Source URL: https://www.biotech.iisuniv.ac.in/courses/UG-Courses/B.Sc%28Elective%29/APPLIED-MICROBIOLOGY/IMMUNOLOGY

Links:
[1] https://www.biotech.iisuniv.ac.in/courses/UG-Courses/B.Sc%28Elective%29/APPLIED-MICROBIOLOGY/IMMUNOLOGY
[2] https://www.biotech.iisuniv.ac.in/academic-year/2018-2019